CVS Revision part -3 Cardiac cycle

                     CVS Revision part -3  Cardiac cycle


Mechanical events in the cardiac cycle 

1.Late diastole
2.Atrial systole
3.Ventricular systole
a.Isometric ventricular contraction
b.Ventricular Ejection
4. Early diastole
a.protodiastole
b.Isovolumetric ventricular relaxation




Late diastole
  • Atrioventricular valves opened, aortic and pulmonary are closed 
  • Blood flow into heart fills both atria and ventricles 
  • Rate of filling declines as ventricles distend 
  • The cusps of the AV valves drift towards closure 
  • Pressure remains low 
  • 70 % of filling occur 
Atrial systole
  • Atrial musculature contracts and propels additional blood to ventricles 
  • Opening of SVC, IVC and pulmonary veins narrows , but some regurgitation occurs 
Ventricular systole

a.Isovolumetric ventricular contraction (0.05 S)
  • AV values closed 
  • Ventricular musculature shortens relatively little 
  • Pressure rises sharply until it exceeds the pressure in the aorta and pulmonary trunk 
  • AV value bulges towards atria, increasing atrial pressure 

b. Ventricular ejection
  • Ventricular pressure has now exceeded aortic and pulmonary arterial pressure 
  • So, semilunar valves open and ejection begins 
  • Rapid at first. Slow down late 
  • AV valves are pulled down by the contraction of ventricular muscle and atrial pressure drops 
  • Inter- ventricular pressure rises to its maximum and decline somewhat until it reaches the end of ventricular systole 
  •  Amount of blood ejected approximately 70 ml 
4. Early diastole 

a.Protodiastole ( 0.04 S )
  • Ventricular muscle is fully contracted 
  • Already falling ventricular pressure drops more rapidly 
  • In ends when the momentum of ejected blood is overcome 
  • Semilunar valves close marking the end of ventricular systole 
b.Isovolumetric ventricular relaxation
  • Both AV and semilunar valves are closed 
  • Pressure in ventricles continues to drop rapidly 
  • Atria in diastole are filling and atrial pressure increases 
  • Ends when ventricular pressure falls below atrial pressure and AV valves open, permitting ventricles to fill 
Rapid ventricular filling
  • Once AV node valves open, blood accumulated in atria rapidly into the ventricles. 
  • Rate decrease as ventricles fills 
Timing of events in cardiac cycles 
  •  Similar on both sides, but take place at different times 
  • Right atrium starts to contract before the left 
  • Right ventricular starts to contract after the left 
  • However the pulmonary arterial pressure is lower than aortic pressure, So 
  • Right ventricular ejection begins before left ventricular ejection 
  • Resistance of the pulmonary vascular tree becomes lower in inspiration, so 
  • Pulmonary and aortic valves close almost at the same time during expiration 
  • But, aortic valve close before pulmonary valve at inspiration 
  • When measured over a period of time, the outputs of two ventricles are equal 


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